Humalog may interact with albuterol, clonidine, reserpine, guanethidine, or betablockers. May be diluted with sterile diluent for humalog, humulin n, humulin 5050, humulin 7030, and nph ilentin to a concentration of 1. Atkinson, in williams textbook of endocrinology thirteenth edition, 2016. Find patient medical information for insulin lispro subcutaneous on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. You most likely will find some helpful info in this post, come have a peek. Insulin, regular injection, concentrated daviss drug guide for. When using these pens, prime the pen after attaching a new needle and before each injection to assure an accurate dose is administered. Many other medicines can increase or decrease the effects of insulin lispro on lowering blood sugar. The centers for disease control estimates as many as 29 million americans struggle with the disease, making humalog a lifesaving medication. Insulin lispro protamine suspension ilps is a protaminebased, intermediateacting insulin formulation of the shortacting analog insulin lispro. Find information on insulin lispro, rdna origin admelog, humalog in davis s drug guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Review of insulin therapy and pen use in hospitalized patients. Also, insulin helps us store energy that we can use later. Ilps has been predominantly used as the basal insulin component of.
Food and drug administration 10903 new hampshire avenue silver spring, md 20993 1888infofda 18884636332 contact fda. Humalog for subcutaneous injection should not be mixed with insulin preparations other than nph insulin. If humalog is mixed with nph insulin, humalog should be drawn into the syringe first. Specific information for insulin lispro should be followed for inuse. Humalog u100 continuous subcutaneous infusion route insulin pump do not mix. Never share a humalog, insulin lispro injection, humalog mix7525, or humalog mix5050 prefilled pen, cartridge, reusable pen compatible with lilly 3 ml cartridges, or syringe between patients, even if the needle is changed. Avoid additional harm when using insulin and dextrose authors staley lawes, pharmd, bcps, fismp patient safety analyst. Humalog insulin lispro injection, usp rdna origin for injection. Insulin lispro injection is a rapidacting human insulin analog. Implement aerobic exercise and endurance training programs to maintain optimal body weight, improve insulin sensitivity, and reduce the risk of macrovascular disease heart attack, stroke and microvascular problems reduced blood flow to tissues and organs that causes poor wound healing, neuropathy, retinopathy, and nephropathy.
Humalog u100 may be mixed with nph insulin preparations. Eli lilly and company, indianapolis, in for hospital use. Dailymed humalog insulin lispro injection, solution. Rotate the spot where you give your insulin to prevent swelling, lumps, and scar tissue. The harriet lane handbook app and website provides pediatric diagnosis and treatment, pediatric management algorithms, and pediatric drug formulary from. Insulin lispro, of recombinant dna origin, is a human insulin analogue created by reversal of the amino acids at positions 28 and 29 on the human insulin b chain. Mixing two insulins since your doctor has ordered 2 kinds of insulin that can be mixed, you need to learn how to. Caution patient that insulin pens should not be shared with others, even if clean needlesareused. If humalog u100 is mixed with nph insulin, humalog u100 should be drawn into the syringe first. Humalog insulin lispro injection, for subcutaneous or. Insulin is a hormone that works by lowering levels of glucose sugar in the blood. Humulin r, insulintoronto, novolin r, humulin r regular u500. Thus humalog can be injected right before a meal, or even immediately after a meal.
It is a rapidacting insulin prescribed to help control blood sugar spikes that occur after you eat. Insulin lispro differs from human insulin in that the amino acid proline at position b28 is replaced by lysine and the. Humalog insulin lispro injection is a rapidacting human insulin. This information does not take the place of talking to your healthcare provider about your medical condition or your treatment. Drug information table insulin lispro humalog, regular. Lora kleis, andrew wood, chad parkes, michael wood, alan davis. Insulin lispro is produced by recombinant dna technology utilizing a nonpathogenic laboratory strain of escherichia coli.
Humalog insulin lispro is a fastacting insulin that starts to work about 15 minutes after injection, peaks in about 1 hour, and keeps working for 2 to 4 hours. Insulin lispro is a fastacting insulin that starts to work about 15 minutes after injection, peaks in about 1 hour, and keeps working for 2 to 4 hours insulin lispro is used to improve blood sugar control in adults and children with diabetes mellitus insulin lispro is used to treat type 2 diabetes in. Humalog mix5050 insulin lispro injection, suspension humalog mix5050 kwikpen insulin lispro injection, suspension if this spl contains inactivated ndcs listed by the fda initiated compliance action, they will be specified as such. Capitals indicate life threatening, underlines indicate most frequent. Insulin lispro humalog r is such an analogue which has gained regulatory approval for general. Insulin lispro diluted to u10 or u50 using sterile diluent for humalog may be stored for up to 28 days at 5 degrees c 41 degrees f and for 14 days at 30 degrees c 86 degrees f. Available for use in a prefilled pen humalog kwikpen. Insulin, regular injection, concentrated daviss drug.
Patients using vials must never share needles or syringes with another person. Dosage adjustment may be needed when switching from another insulin to humalog see warnings and precautions 5. Humalog is used to improve blood sugar control in adults and children with diabetes mellitus. Humalog is a rapid acting human insulin analog indicated to. Drug information table insulin lispro humalog, regular humulin r, nph humulin n, insulin glargine lantus therapeutic use administration health care professional administration patient diabetes mellitus type 1, type 2, gestational injection considerations give subcutaneously using an insulin syringe or iv humulin r. Humalog is a brand name for insulin lispro, which is a. This is done by using the glucose in the blood as quick energy. Humalog mix 7525, and humalog mix 5050, contain mixtures of insulin lispro along with a second form of insulin called lispro protamine. Side effects of humalog insulin lispro human analog. It is used by injection under the skin or within an insulin pump. Insulin is one of many hormones that help the body turn the food we eat into energy. Explain to patient that this medication controls hyperglycemia but does not cure.
Admelog, humalog insulin lispro dosing, indications. Onset of effects typically occurs within 30 minutes and lasts about 5 hours. Insulin lispro lysb28, prob29 human insulin is formed by switching lysine and proline amino acids at positions b28 and b29 figure 1. Find information on insulin mixtures humalog mix 7525, novolog mix 7030 in davis s drug guide including dosage, side effects, interactions, nursing implications, mechanism of action, half life, administration, and more. Instructions for mixing with other insulins humalog u100subcutaneousinjectionroute humalog u100 maybe mixed with nph insulin preparations only.
Insulin lispro protamine suspension ilps and insulin detemir were compared in insulinnaive patients with type 2 diabetes poorly controlled by oral. When you have diabetes mellitus, your body cannot make enough or does not use insulin properly. Insulin lispro, rdna origin admelog, humalog daviss drug guide. Comparison of the effect of insulin glulisine to insulin aspart on. Efficacy and safety of insulin lispro protamine suspension. Insulin lispro, rdna origin admelog, humalog daviss. Humalog u100 and u200 kwikpens are designed to dial doses in increments of 1 unit.
Find information on insulin lispro, rdna origin admelog, humalog in daviss drug guide including dosage, side effects, interactions. Insulin lispro was the first insulin analogue to receive approval by the u. Insulin needs may be altered during stress, major illness, or changes in exercise, meal patterns, or coadministered drugs. Taking insulin or other diabetes medicines is often part of dealing with diabetes in addition to healthy food choices and physical activity, medicine can help you manage the illness. To view the entire topic, please sign in or purchase a subscription. Well compare how these drugs treat diabetes, what their side effects are, and more. Humalog starts to work almost immediately, compared to regular insulin which requires about 30 minutes to begin to work. Insulin lispro, sold under the brand name humalog among others, is a type of insulin used to treat type i and type ii diabetes. Insulin lispro reference guide for safe and effective use from the american society of. By the mid1980s, efforts to develop insulin analogues displaying improved therapeutic properties were well underway. The cartridge should not be refilled with insulin of any type, including insulin lispro. Doses between 5 and 20 units of insulin administered intravenously as. Humalog is the brandname version of insulin lispro, and novolog is the brandname version of insulin aspart. Check the labels on the insulin bottles to make sure you have the correct insulin.
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